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Association of lipoprotein(a) and LPA gene with calcific aortic valve disease

22 Aug 2025

Abstract excerpt

OBJECTIVE: To investigate the association between Lp(a) levels and calcific aortic valve disease (CAVD) and the potential molecular mechanism underlying the effect of LPA gene expression on aortic valve calcification (AVC). METHODS: Case-control and cohort studies on the association between Lp(a) and CAVD were searched in the meta-analysis. Meta-analysis was performed using RevMan and Stata. AVC-related gene...

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PMID: 40847316
DOI: 10.1186/s40001-025-03071-8

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