Article
What can we learn from DNA methylation studies in lupus?
Clinical immunology (Orlando, Fla.) - 1 Jan 2022
Ferreté-Bonastre Anna Guiomar, Cortés-Hernández Josefina, Ballestar Esteban
Abstract excerpt
During the past twenty years, a wide range of studies have established the existence of epigenetic alterations, particularly DNA methylation changes, in lupus. Epigenetic changes might have different contributions in children-onset versus adult-onset lupus. DNA methylation alterations have been identified and characterized in relation to disease activity and damage, different lupus subtypes and responses to...
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