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New insights into the genic and metabolic characteristics of induced pluripotent stem cells from polycystic ovary syndrome women

9 Aug 2018

Abstract excerpt

BACKGROUND: Polycystic ovary syndrome (PCOS) is a common endocrine and metabolic disorder that affects female fertility. However, with the lack of a corresponding research model, the pathology mechanism of PCOS is poorly understood. Induced pluripotent stem cell (iPSC) technology has been recognized as means to generate patient-specific stem cells for disease modeling. METHODS: The mRNA abundance of iPSCs was...

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PMID: 30092830
DOI: 10.1186/s13287-018-0950-x

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