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Mitochondrial regulation in human pluripotent stem cells during reprogramming and β cell differentiation

20 Oct 2023

Abstract excerpt

Mitochondria are the powerhouse of the cell and dynamically control fundamental biological processes including cell reprogramming, pluripotency, and lineage specification. Although remarkable progress in induced pluripotent stem cell (iPSC)-derived cell therapies has been made, very little is known about the role of mitochondria and the mechanisms involved in somatic cell reprogramming into iPSC and directed...

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PMID: 37929027
DOI: 10.3389/fendo.2023.1236472

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