Article

Bulk RNA-Sequencing of small airway cell cultures from IPF and post-COVID lung fibrosis patients illustrates disease signatures and differential responses to TGF- <i>β</i> 1 treatment

2023-03-01

Abstract excerpt

IPF is a condition in which an injury to the lung leads to the accumulation of scar tissue. This fibrotic tissue reduces lung compliance and impairs gas exchange. Studies have shown that infection with COVID-19 significantly worsens the clinical outcomes of IPF patients. The exact etiology of IPF is unknown, but recent evidence suggests that the distal small airways, (those having a diameter less than 2 mm in adul...

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Literature Corpus work: c70926a1-dfcf-505d-a556-c79b076190ce
DOI: 10.1101/2023.03.01.530431

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