Article
A Major Mycobacterium tuberculosis outbreak caused by one specific genotype in a low-incidence country: Exploring gene profile virulence explanations.
Scientific reports - 8 Aug 2018
Folkvardsen Dorte Bek, Norman Anders, Andersen Åse Bengård, Rasmussen Erik Michael, Lillebaek Troels, Jelsbak Lars
Abstract excerpt
Denmark, a tuberculosis low burden country, still experiences significant active Mycobacterium tuberculosis (Mtb) transmission, especially with one specific genotype named Cluster 2/1112-15 (C2), the most prevalent lineage in Scandinavia. In addition to environmental factors, antibiotic resistance, and human genetics, there is increasing evidence that Mtb strain variation plays a role for the outcome of infection...
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