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Article

Association between two-component systems gene mutation and Mycobacterium tuberculosis transmission revealed by whole genome sequencing.

BMC genomics - 28 Nov 2023

Li Yameng, Kong Xianglong, Li Yifan, Tao Ningning, Hou Yawei, Wang Tingting, Li Yingying, Han Qilin, Liu Yao, Li Huaichen

Abstract excerpt

BACKGROUND: Two-component systems (TCSs) assume a pivotal function in Mycobacterium tuberculosis (M.tuberculosis) growth. However, the exact regulatory mechanism of this system needs to be elucidated, and only a few studies have investigated the effect of gene mutations within TCSs on M.tuberculosis transmission. This research explored the relationship between TCSs gene mutation and the global transmission of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 38017383
DOI: 10.1186/s12864-023-09788-2
PMCID: PMC10683263

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