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Article

Force and scleraxis synergistically promote the commitment of human ES cells derived MSCs to tenocytes

14 Dec 2012

Abstract excerpt

As tendon stem/progenitor cells were reported to be rare in tendon tissues, tendons as vulnerable targets of sports injury possess poor self-repair capability. Human ESCs (hESCs) represent a promising approach to tendon regeneration. But their teno-lineage differentiation strategy has yet to be defined. Here, we report that force combined with the tendon-specific transcription factor scleraxis synergistically...

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PMID: 23243495
DOI: 10.1038/srep00977

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Force and scleraxis synergistically promote the commitment of human ES cells derived MSCs to tenocytesPMID 23243495Read ↗

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