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Article

Unravelling the GSK3β-related genotypic interaction network influencing hippocampal volume in recurrent major depressive disorder.

Psychiatric genetics - 1 Oct 2018

Inkster Becky, Simmons Andy, Cole James H, Schoof Erwin, Linding Rune, Nichols Tom, Muglia Pierandrea, Holsboer Florian, Sämann Philipp G, McGuffin Peter, Fu Cynthia H Y, Miskowiak Kamilla, Matthews Paul M, Zai Gwyneth, Nicodemus Kristin

Abstract excerpt

OBJECTIVE: Glycogen synthase kinase 3β (GSK3β) has been implicated in mood disorders. We previously reported associations between a GSK3β polymorphism and hippocampal volume in major depressive disorder (MDD). We then reported similar associations for a subset of GSK3β-regulated genes. We now investigate an algorithm-derived comprehensive list of genes encoding proteins that directly interact with GSK3β to...

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Identifiers

PMID: 30080747
DOI: 10.1097/YPG.0000000000000203
PMCID: PMC6531290

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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