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Article

Recurrent major depression and right hippocampal volume: A bivariate linkage and association study.

Human brain mapping - 1 Jan 2016

Mathias Samuel R, Knowles Emma E M, Kent Jack W, McKay D Reese, Curran Joanne E, de Almeida Marcio A A, Dyer Thomas D, Göring Harald H H, Olvera Rene L, Duggirala Ravi, Fox Peter T, Almasy Laura, Blangero John, Glahn David C

Abstract excerpt

Previous work has shown that the hippocampus is smaller in the brains of individuals suffering from major depressive disorder (MDD) than those of healthy controls. Moreover, right hippocampal volume specifically has been found to predict the probability of subsequent depressive episodes. This study explored the utility of right hippocampal volume as an endophenotype of recurrent MDD (rMDD). We observed a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 26485182
DOI: 10.1002/hbm.23025
PMCID: PMC4981180

Genes

DLGAP1
SMCHD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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