Clinical Manifestations and Long-Term Mortality in Lamin A/C Mutation Carriers From a Japanese Multicenter Registry.

doi:10.1253/circj.CJ-18-0339

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Article

Clinical Manifestations and Long-Term Mortality in Lamin A/C Mutation Carriers From a Japanese Multicenter Registry.

Circulation journal : official journal of the Japanese Circulation Society - 25 Oct 2018

Nakajima Kenzaburo, Aiba Takeshi, Makiyama Takeru, Nishiuchi Suguru, Ohno Seiko, Kato Koichi, Yamamoto Yuta, Doi Takahiro, Shizuta Satoshi, Onoue Kenji, Yagihara Nobue, Ishikawa Taisuke, Watanabe Ichiro, Kawakami Hiroshi, Oginosawa Yasushi, Murakoshi Nobuyuki, Nogami Akihiko, Aonuma Kazutaka, Saito Yoshihiko, Kimura Takeshi, Yasuda Satoshi, Makita Naomasa, Shimizu Wataru, Horie Minoru, Kusano Kengo

Abstract excerpt

BACKGROUND: Mutation in the lamin A/C gene (LMNA) is associated with several cardiac phenotypes, such as cardiac conduction disorders (CCD), atrial arrhythmia (AA), malignant ventricular arrhythmia (MVA) and left ventricular dysfunction (LVD), leading to sudden cardiac death (SCD) and/or end-stage heart failure. We investigated how these phenotypes are associated with each other and which of them are most...

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PMID: 30078822
DOI: 10.1253/circj.CJ-18-0339

Genes

LMNA
SCD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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