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Article

A novel mutation in lamin a/c causing familial dilated cardiomyopathy associated with sudden cardiac death.

Journal of cardiac failure - 1 Mar 2015

Pérez-Serra Alexandra, Toro Rocío, Campuzano Oscar, Sarquella-Brugada Georgia, Berne Paola, Iglesias Anna, Mangas Alipio, Brugada Josep, Brugada Ramon

Abstract excerpt

BACKGROUND: Dilated cardiomyopathy (DCM), a cardiac heterogeneous pathology characterized by left ventricular or biventricular dilatation, is a leading cause of heart failure and heart transplantation. The genetic origin of DCM remains unknown in most cases, but >50 genes have been associated with DCM. We sought to identify the genetic implication and perform a genetic analysis in a Spanish family affected by DCM...

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Share to Amino Acid Sequence
Share to Cardiomyopathy, Dilated

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Child, Preschool

Share to Death, Sudden, Cardiac

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Share to Lamin Type A

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Source

Identifiers

PMID: 25498755
DOI: 10.1016/j.cardfail.2014.12.003

Genes

LMNA

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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