Article
Implantable cardioverter-defibrillators in lamin A/C mutation carriers with cardiac conduction disorders.
Heart rhythm - 1 Oct 2013
Anselme Frédéric, Moubarak Ghassan, Savouré Arnaud, Godin Bénédicte, Borz Bogdan, Drouin-Garraud Valérie, Gay Arnaud
Abstract excerpt
BACKGROUND: Sudden cardiac death is frequent in patients with lamin A/C gene (LMNA) mutations and may be related to ventricular arrhythmias (VA). OBJECTIVE: To evaluate a strategy of prophylactic implantable cardioverter-defibrillator (ICD) implantation in LMNA mutation carriers with significant cardiac conduction disorders. METHODS: Forty-seven consecutive patients (mean age 38 ± 11 years; 26 men) were...
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