Article
Long-Term Arrhythmic and Nonarrhythmic Outcomes of Lamin A/C Mutation Carriers.
Journal of the American College of Cardiology - 29 Nov 2016
Kumar Saurabh, Baldinger Samuel H, Gandjbakhch Estelle, Maury Philippe, Sellal Jean-Marc, Androulakis Alexander F A, Waintraub Xavier, Charron Philippe, Rollin Anne, Richard Pascale, Stevenson William G, Macintyre Ciorsti J, Ho Carolyn Y, Thompson Tina, Vohra Jitendra K, Kalman Jonathan M, Zeppenfeld Katja, Sacher Frederic, Tedrow Usha B, Lakdawala Neal K
Abstract excerpt
BACKGROUND: Mutations in LMNA are variably expressed and may cause cardiomyopathy, atrioventricular block (AVB), or atrial arrhythmias (AAs) and ventricular arrhythmias (VA). Detailed natural history studies of LMNA-associated arrhythmic and nonarrhythmic outcomes are limited, and the prognostic significance of the index cardiac phenotype remains uncertain. OBJECTIVES: This study sought to describe the arrhythmic...
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