Article
Meta-analysis of clinical characteristics of 299 carriers of LMNA gene mutations: do lamin A/C mutations portend a high risk of sudden death?
Journal of molecular medicine (Berlin, Germany) - 1 Jan 2005
van Berlo Jop H, de Voogt Willem G, van der Kooi Anneke J, van Tintelen J Peter, Bonne Gisèle, Yaou Rabah Ben, Duboc Denis, Rossenbacker Tom, Heidbüchel Hein, de Visser Marianne, Crijns Harry J G M, Pinto Yigal M
Abstract excerpt
This study evaluated common clinical characteristics of patients with lamin A/C gene mutations that cause either isolated dilated cardiomyopathy or dilated cardiomyopathy in association with skeletal muscular dystrophy. We pooled clinical data of all published carriers of lamin A/C gene mutations as cause of skeletal and/or cardiac muscle disease and reviewed ECG findings. Cardiac dysrhythmias were reported in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.