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Article

Hair Cell Mechanotransduction Regulates Spontaneous Activity and Spiral Ganglion Subtype Specification in the Auditory System.

Cell - 23 Aug 2018

Sun Shuohao, Babola Travis, Pregernig Gabriela, So Kathy S, Nguyen Matthew, Su Shin-San M, Palermo Adam T, Bergles Dwight E, Burns Joseph C, Müller Ulrich

Abstract excerpt

Type I spiral ganglion neurons (SGNs) transmit sound information from cochlear hair cells to the CNS. Using transcriptome analysis of thousands of single neurons, we demonstrate that murine type I SGNs consist of subclasses that are defined by the expression of subsets of transcription factors, cell adhesion molecules, ion channels, and neurotransmitter receptors. Subtype specification is initiated prior to the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 30078710
DOI: 10.1016/j.cell.2018.07.008
PMCID: PMC6429032

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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