Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of the Kv1 family of K+ channels and their functional blueprint in the properties of auditory neurons as revealed by genetic and functional analyses.

Journal of neurophysiology - 1 Oct 2013

Wang Wenying, Kim Hyo Jeong, Lv Ping, Tempel Bruce, Yamoah Ebenezer N

Abstract excerpt

Developmental plasticity in spiral ganglion neurons (SGNs) ensues from profound alterations in the functional properties of the developing hair cell (HC). For example, prehearing HCs are spontaneously active. However, at the posthearing stage, HC membrane properties transition to graded receptor potentials. The dendrotoxin (DTX)-sensitive Kv1 channel subunits (Kv1.1, 1.2, and 1.6) shape the firing properties and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Action Potentials
Share to Hair Cells, Auditory

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Membrane Potentials

Share to Mutation

Share to Protein Multimerization

Share to Protein Subunits

Source

Open in PubMed Open full text

Identifiers

PMID: 23864368
DOI: 10.1152/jn.00290.2013
PMCID: PMC3798938

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of the Kv1 family of K+ channels and their functional blueprint in the properties of auditory neurons as revealed by genetic and functional analyses.PMID 23864368Read ↗

Kv4, Kv2, and Kv3 currents shape intrinsic lateral olivocochlear excitability independent of hair cell dysfunction during development and ageingSemantic proximity Read ↗

Etiology of distinct membrane excitability in pre- and posthearing auditory neurons relies on activity of Cl- channel TMEM16A.Semantic proximity Read ↗

Gating of hair cell Ca <sup>2+</sup> channels governs the activity of cochlear neuronsSemantic proximity Read ↗

Seizures and reduced life span in mice lacking the potassium channel subunit Kv1.2, but hypoexcitability and enlarged Kv1 currents in auditory neurons.Semantic proximity Read ↗

Hyperexcitability and reduced low threshold potassium currents in auditory neurons of mice lacking the channel subunit Kv1.1.Semantic proximity Read ↗

Kv7-type channel currents in spiral ganglion neurons: involvement in sensorineural hearing loss.Semantic proximity Read ↗

Voltage-gated potassium channels and the diversity of electrical signalling.Semantic proximity Read ↗

Genetic perturbations suggest a role of the resting potential in regulating the expression of the ion channels of the KCNA and HCN families in octopus cells of the ventral cochlear nucleus.Semantic proximity Read ↗

Hair Cell Mechanotransduction Regulates Spontaneous Activity and Spiral Ganglion Subtype Specification in the Auditory System.Semantic proximity Read ↗

Functional contributions of HCN channels in the primary auditory neurons of the mouse inner ear.Semantic proximity Read ↗

Developmental refinement of hair cell synapses tightens the coupling of Ca2+ influx to exocytosis.Semantic proximity Read ↗

Concurrent maturation of inner hair cell synaptic Ca2+ influx and auditory nerve spontaneous activity around hearing onset in mice.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.