Article
Production of microhomologous-mediated site-specific integrated LacS gene cow using TALENs.
Theriogenology - 1 Oct 2018
Su Xiaohu, Wang Shenyuan, Su Guanghua, Zheng Zhong, Zhang Jiaqi, Ma Yunlong, Liu Zongzheng, Zhou Huanmin, Zhang Yanru, Zhang Li
Abstract excerpt
Gene editing tools (Zinc-Finger Nucleases, ZFN; Transcription Activator-Like Effector Nucleases, TALEN; and Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/CRISPR-associated (Cas)9, CRISPR-Cas9) provide us with a powerful means of performing genetic engineering procedures. A combinational approach that utilizes both somatic cell nuclear transfer (SCNT) and somatic cell gene editing facilitates...
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