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Article

Role of stem cells in large animal genetic engineering in the TALENs-CRISPR era.

Reproduction, fertility, and development - 1 Jan 2013

Park Ki-Eun, Telugu Bhanu Prakash V L

Abstract excerpt

The establishment of embryonic stem cells (ESCs) and gene targeting technologies in mice has revolutionised the field of genetics. The relative ease with which genes can be knocked out, and exogenous sequences introduced, has allowed the mouse to become the prime model for deciphering the genetic code. Not surprisingly, the lack of authentic ESCs has hampered the livestock genetics field and has forced animal...

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PMID: 24305178
DOI: 10.1071/RD13258

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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