Article
Comparison of DNA extraction methods for drug susceptibility testing by allele-specific primer extension on a microsphere-based platform: Chelex-100 (in-house and commercialized) and MagPurix TB DNA Extraction Kit.
Journal of microbiological methods - 1 Sept 2018
Kang Minji, Yang Jeong Seong, Kim Yoojeong, Kim Kyungjong, Choi Hongjo, Lee Seung Heon
Abstract excerpt
Tuberculosis (TB), caused by infections of the Mycobacterium tuberculosis (MTB) complex, is the ninth leading cause of death worldwide, and several molecular approaches for MTB species identification and the detection of mutations associated with drug resistance have been developed to date. We previously developed a diagnostic assay for drug susceptibility testing that can detect mutations conferring resistance...
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