Article
Magnetic barcode assay for genetic detection of pathogens.
Nature communications - 1 Jan 2013
Liong Monty, Hoang Anh N, Chung Jaehoon, Gural Nil, Ford Christopher B, Min Changwook, Shah Rupal R, Ahmad Rushdy, Fernandez-Suarez Marta, Fortune Sarah M, Toner Mehmet, Lee Hakho, Weissleder Ralph
Abstract excerpt
The task of rapidly identifying patients infected with Mycobacterium tuberculosis in resource-constrained environments remains a challenge. A sensitive and robust platform that does not require bacterial isolation or culture is critical in making informed diagnostic and therapeutic decisions. Here we introduce a platform for the detection of nucleic acids based on a magnetic barcoding strategy. PCR-amplified...
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