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Article

Detection of first-line anti-tuberculosis drug resistance mutations by allele-specific primer extension on a microsphere-based platform.

Annals of laboratory medicine - 1 Sept 2015

Lee Seung Heon, Choi Hee Baeg, Yu Sung Yul, Chang Uck Jin, Kim Chang Ki, Kim Hee Jin

Abstract excerpt

BACKGROUND: Resistance of Mycobacterium tuberculosis to anti-tuberculosis (TB) drugs is almost exclusively due to spontaneous chromosomal mutations in target genes. Rapid detection of drug resistance to both first- and second-line anti-TB drugs has become a key component of TB control programs. Technologies that allow rapid, cost-effective, and high-throughput detection of specific nucleic acid sequences are...

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Share to Antitubercular Agents
Share to Drug Resistance, Multiple, Bacterial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Tuberculosis, Multidrug-Resistant

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Identifiers

PMID: 26206684
DOI: 10.3343/alm.2015.35.5.487
PMCID: PMC4510500

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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