Article
Traffic-Related Air Pollution, APOEε4 Status, and Neurodevelopmental Outcomes among School Children Enrolled in the BREATHE Project (Catalonia, Spain).
Environmental health perspectives - 1 Aug 2018
Alemany Silvia, Vilor-Tejedor Natàlia, García-Esteban Raquel, Bustamante Mariona, Dadvand Payam, Esnaola Mikel, Mortamais Marion, Forns Joan, van Drooge Barend L, Álvarez-Pedrerol Mar, Grimalt Joan O, Rivas Ioar, Querol Xavier, Pujol Jesus, Sunyer Jordi
Abstract excerpt
BACKGROUND: Traffic-related air pollution is emerging as a risk factor for Alzheimer's disease (AD) and impaired brain development. Individual differences in vulnerability to air pollution may involve the ε4 allele of Apolipoprotein E (APOE) gene, the primary genetic risk factor for AD. OBJECTIVE: We analyzed whether the association between traffic air pollution and neurodevelopmental outcomes is modified by...
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