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Article

A Glutamate Transporter EAAT1 Gene Variant Influences Amygdala Functional Connectivity in Bipolar Disorder.

Journal of molecular neuroscience : MN - 1 Aug 2018

Poletti Sara, Riberto Martina, Vai Benedetta, Ghiglino Davide, Lorenzi Cristina, Vitali Alice, Brioschi Silvia, Locatelli Clara, Serretti Alessandro, Colombo Cristina, Benedetti Francesco

Abstract excerpt

Bipolar disorder (BD) is a severe illness characterized by recurrent depressive and manic episodes and by emotional dysregulation. Altered cortico-limbic connectivity could account for typical symptoms of the disorder such as mood instability, emotional dysregulation, and cognitive deficits. Functional connectivity positively associated with glutamatergic neurotransmission. The inactivation of glutamate is...

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PMID: 30073554
DOI: 10.1007/s12031-018-1138-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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