Article
Variation of the gene coding for DARPP-32 (PPP1R1B) and brain connectivity during associative emotional learning.
NeuroImage - 16 Jan 2012
Curčić-Blake Branislava, Swart Marte, Ter Horst Gert J, Langers Dave R M, Kema Ido P, Aleman André
Abstract excerpt
Associative emotional learning, which is important for the social emotional functioning of individuals and is often impaired in psychiatric illnesses, is in part mediated by dopamine and glutamate pathways in the brain. The protein DARPP-32 is involved in the regulation of dopaminergic and glutaminergic signaling. Consequently, it has been suggested that the haplotypic variants of the gene PPP1R1B that encodes...
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