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Article

Uncovering Natural Longevity Alleles from Intercrossed Pools of Aging Fission Yeast Cells.

Genetics - 1 Oct 2018

Ellis David A, Mustonen Ville, Rodríguez-López María, Rallis Charalampos, Malecki Michał, Jeffares Daniel C, Bähler Jürg

Abstract excerpt

Quantitative traits often show large variation caused by multiple genetic factors . One such trait is the chronological lifespan of non-dividing yeast cells, serving as a model for cellular aging. Screens for genetic factors involved in aging typically assay mutants of protein-coding genes. To identify natural genetic variants contributing to cellular aging, we exploited two strains of the fission yeast,...

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Identifiers

PMID: 30072377
DOI: 10.1534/genetics.118.301262
PMCID: PMC6216586

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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