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Article

Dietary modulation of mitochondrial DNA damage: implications in aging and associated diseases.

The Journal of nutritional biochemistry - 1 Jan 2019

Lam Juwela, McKeague Maureen

Abstract excerpt

Mammalian mitochondria contain small genomes [mitochondrial DNA (mtDNA)], which encode several of the proteins that are crucial for respiration. As such, maintaining the integrity of mtDNA is essential for healthy life. Nutritional strategies such as "Calorie Restriction" may play an important role in regulating mtDNA integrity and prolonging lifespan. In this review, we compare mtDNA with nuclear DNA damage and...

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Identifiers

PMID: 30071405
DOI: 10.1016/j.jnutbio.2018.07.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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