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Article

Selection-driven cost-efficiency optimization of transcripts modulates gene evolutionary rate in bacteria.

Genome biology - 31 Jul 2018

Seward Emily A, Kelly Steven

Abstract excerpt

BACKGROUND: Most amino acids are encoded by multiple synonymous codons. However, synonymous codons are not used equally, and this biased codon use varies between different organisms. It has previously been shown that both selection acting to increase codon translational efficiency and selection acting to decrease codon biosynthetic cost contribute to differences in codon bias. However, it is unknown how these two...

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Identifiers

PMID: 30064467
DOI: 10.1186/s13059-018-1480-7
PMCID: PMC6066932

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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