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Article

Associations of iron metabolism genes with blood manganese levels: a population-based study with validation data from animal models.

Environmental health : a global access science source - 10 Nov 2011

Claus Henn Birgit, Kim Jonghan, Wessling-Resnick Marianne, Téllez-Rojo Martha María, Jayawardene Innocent, Ettinger Adrienne S, Hernández-Avila Mauricio, Schwartz Joel, Christiani David C, Hu Howard, Wright Robert O

Abstract excerpt

BACKGROUND: Given mounting evidence for adverse effects from excess manganese exposure, it is critical to understand host factors, such as genetics, that affect manganese metabolism. METHODS: Archived blood samples, collected from 332 Mexican women at delivery, were analyzed for manganese. We evaluated associations of manganese with functional variants in three candidate iron metabolism genes: HFE...

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Source

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Identifiers

PMID: 22074419
DOI: 10.1186/1476-069X-10-97
PMCID: PMC3248860

Genes

HFE
ALAD
TF

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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