Article
Polymorphisms in iron homeostasis genes and urinary cadmium concentrations among nonsmoking women in Argentina and Bangladesh.
Environmental health perspectives - 1 Apr 2013
Rentschler Gerda, Kippler Maria, Axmon Anna, Raqib Rubhana, Ekström Eva-Charlotte, Skerfving Staffan, Vahter Marie, Broberg Karin
Abstract excerpt
BACKGROUND: Cadmium (Cd) is a human toxicant and carcinogen. Genetic variation might affect long-term accumulation. Cd is absorbed via iron transporters. OBJECTIVES: We evaluated the impact of iron homeostasis genes [divalent metal transporter 1 (SLC11A2), transferrin (TF), transferrin receptors (TFR2 and TFRC), and ferroportin (SLC40A1)] on Cd accumulation. METHODS: Subjects were nonsmoking women living in the...
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