Article
The GCKR rs780094 polymorphism is associated with susceptibility of type 2 diabetes, reduced fasting plasma glucose levels, increased triglycerides levels and lower HOMA-IR in Japanese population.
Journal of human genetics - 1 Sept 2010
Onuma Hiroshi, Tabara Yasuharu, Kawamoto Ryuichi, Shimizu Ikki, Kawamura Ryoichi, Takata Yasunori, Nishida Wataru, Ohashi Jun, Miki Tetsuro, Kohara Katsuhiko, Makino Hideichi, Osawa Haruhiko
Abstract excerpt
It was recently reported that GCKR rs780094 was associated with fasting plasma glucose (FPG) and triglyceride (TG) levels in various ethnic populations (A allele for low FPG and high TG). An association between GCKR rs780094 and type 2 diabetes mellitus (T2DM) (A allele for low risk) has also been reported. We examined the association between GCKR rs780094 and T2DM in Japanese subjects by analyzing 488 cases and...
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