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Article

Subtype-specific signaling pathways and genomic aberrations associated with prognosis of glioblastoma.

Neuro-oncology - 1 Jan 2019

Park Ae Kyung, Kim Pora, Ballester Leomar Y, Esquenazi Yoshua, Zhao Zhongming

Abstract excerpt

Background: A high heterogeneity and activation of multiple oncogenic pathways have been implicated in failure of targeted therapies in glioblastoma (GBM). Methods: Using The Cancer Genome Atlas data, we identified subtype-specific prognostic core genes by a combined approach of genome-wide Cox regression and Gene Set Enrichment Analysis. The results were validated with 8 combined public datasets containing 608...

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Identifiers

PMID: 30053126
DOI: 10.1093/neuonc/noy120
PMCID: PMC6303485

Genes

MET
PCLO

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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