Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Landscape of Genomic Alterations inIDHWild-Type Glioblastoma Identifies PI3K as a Favorable Prognostic Factor

8 Jun 2020

Abstract excerpt

PURPOSE IDH wild-type (WT) glioblastoma (GBM) is an aggressive tumor with poor survival despite current therapies. The aim of this study was to characterize its genomic profile and determine whether a particular molecular signature is associated with improved survival outcomes. PATIENTS AND METHODS Tumor samples from 232 patients with IDH-WT GBM were sequenced, and the landscape of genomic alterations was fully...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromatin Remodeling and Cancer
Share to Ferroptosis and cancer prognosis
Share to Glioma Diagnosis and Treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35050747
DOI: 10.1200/po.19.00385

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Landscape of Genomic Alterations inIDHWild-Type Glioblastoma Identifies PI3K as a Favorable Prognostic FactorPMID 35050747Read ↗

Molecular characterization and survival analysis of a cohort of glioblastoma, IDH-wildtype.Semantic proximity Read ↗

Molecular profiling of CNS tumors for the treatment and management of disease.Semantic proximity Read ↗

Genomic, epigenomic and transcriptomic landscape of glioblastoma.Semantic proximity Read ↗

Distribution differences in prognostic copy number alteration profiles in IDH-wild-type glioblastoma cause survival discrepancies across cohortsSemantic proximity Read ↗

Longitudinal multimodal profiling of IDH-wildtype glioblastoma reveals the molecular evolution and cellular phenotypes underlying prognostically different treatment responsesSemantic proximity Read ↗

Molecular Correlates of Long Survival in IDH-Wildtype Glioblastoma CohortsSemantic proximity Read ↗

New hints towards a precision medicine strategy for IDH wild-type glioblastoma.Semantic proximity Read ↗

Molecular pathology in adult high‐grade gliomas: from molecular diagnostics to target therapiesSemantic proximity Read ↗

Molecular Landscape and Contemporary Prognostic Signatures of GliomasSemantic proximity Read ↗

Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1.Semantic proximity Read ↗

Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1Semantic proximity Read ↗

Integrating genomic, transcriptomic and epigenetic data to identify phenotypically impactful driver pathways in glioblastomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.