Article
Timing somatic events in the evolution of cancer.
Genome biology - 24 Jul 2018
Jolly Clemency, Van Loo Peter
Abstract excerpt
Cancer arises through the accumulation of somatic mutations over time. An understanding of the sequence of events during this process should allow both earlier diagnosis and better prediction of cancer progression. However, the pathways of tumor evolution have not yet been comprehensively characterized. With the advent of whole genome sequencing, it is now possible to infer the evolutionary history of single...
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