Article
Comprehensive assessment of the expression of the SWI/SNF complex defines two distinct prognostic subtypes of ovarian clear cell carcinoma.
Oncotarget - 23 Aug 2016
Abou-Taleb Hisham, Yamaguchi Ken, Matsumura Noriomi, Murakami Ryusuke, Nakai Hidekatsu, Higasa Koichiro, Amano Yasuaki, Abiko Kaoru, Yoshioka Yumiko, Hamanishi Junzo, Koshiyama Masafumi, Baba Tsukasa, Yamada Ryo, Matsuda Fumihiko, Konishi Ikuo, Mandai Masaki
Abstract excerpt
Somatic mutations in the ARID1A tumor-suppressor gene have been frequently identified in ovarian clear cell carcinoma (CCC) cases. BAF250a encoded by ARID1A is a member of the SWI/SNF complex, but the expression and mutation status of other SWI/SNF subunits have not been explored. The current stu...
Topics
- Adenocarcinoma, Clear Cell
- Chromosome Aberrations
- DNA Copy Number Variations
- DNA-Binding Proteins
- Exome
- Female
- Gene Expression Profiling
- Gene Expression Regulation, Neoplastic
- High-Throughput Nucleotide Sequencing