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HDL Cholesterol-Associated Shifts in the Expression of Preselected Genes Reveal both Pro-Atherogenic and Atheroprotective Effects of HDL in Coronary Artery Disease

21 Nov 2024

Abstract excerpt

Background: The associations of high-density lipoprotein (HDL) level and functionality with lipid metabolism, inflammation, and innate immunity in coronary artery disease (CAD) remain controversial. The differential expression of a set of genes related to HDL metabolism (24 genes) and atherogenesis (41 genes) in peripheral blood mononuclear cells (PBMC) from CAD and control patients with varied HDL cholesterol...

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Adipokines, Inflammation, and Metabolic Diseases
Atherosclerosis and Cardiovascular Diseases
Diabetes, Cardiovascular Risks, and Lipoproteins

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39614436
DOI: 10.31083/j.fbl2911396

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