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Article

ABC transporters, atherosclerosis and inflammation.

Atherosclerosis - 1 Aug 2010

Fitzgerald Michael L, Mujawar Zahedi, Tamehiro Norimasa

Abstract excerpt

Atherosclerosis, driven by inflamed lipid-laden lesions, can occlude the coronary arteries and lead to myocardial infarction. This chronic disease is a major and expensive health burden. However, the body is able to mobilize and excrete cholesterol and other lipids, thus preventing atherosclerosis by a process termed reverse cholesterol transport (RCT). Insight into the mechanism of RCT has been gained by the...

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Source

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Identifiers

PMID: 20138281
DOI: 10.1016/j.atherosclerosis.2010.01.011
PMCID: PMC2888932

Genes

ABCA1
ABCG1
ABCG5

Provenance

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