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Article

Genetic and epigenetic regulation of inflammasomes: Role in atherosclerosis.

Atherosclerosis - 1 Sept 2024

Yalcinkaya Mustafa, Tall Alan R

Abstract excerpt

The cardiovascular complications of atherosclerosis are thought to arise from an inflammatory response to the accumulation of cholesterol-rich lipoproteins in the arterial wall. The positive outcome of CANTOS (Canakinumab Anti-inflammatory Thrombosis Outcome Study) provided key evidence to support this concept and suggested that inflammasomes and IL-1β are important inflammatory mediators in human atherosclerotic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Methylation

Share to Epigenesis, Genetic

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Source

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Identifiers

PMID: 39111028
DOI: 10.1016/j.atherosclerosis.2024.118541
PMCID: PMC11374466

Genes

AIM2
ASXL1
DNMT3A
JAK2
NLRP3
TET2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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