Article
Molecular footprints of selective pressure in the neuraminidase gene of currently circulating human influenza subtypes and lineages.
Virology - 1 Sept 2018
Correia Vanessa, Abecasis Ana B, Rebelo-de-Andrade Helena
Abstract excerpt
Influenza neuraminidase (NA) is under selective pressure (SP) of both host immune system and drug use. Here, we assembled large datasets of NA sequences of worldwide circulating viruses to estimate the global and site-specific SP acting on all current subtypes/lineages of human influenza NA. An overall negative SP of similar magnitude and a prevalence of negatively selected sites were observed for all...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
