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Article

Strategies to Reduce Solute Carrier-Mediated Toxicity.

Clinical pharmacology and therapeutics - 1 Nov 2018

Hu Shuiying, Sprowl Jason A

Abstract excerpt

Toxicity is among the greatest concerns during clinical use of drugs, and it has been well documented that transporter proteins facilitate such events by regulating drug accumulation. However, an important question is whether strategies could be adopted to diminish such toxicities. Although the field is currently in its infancy, some examples exist demonstrating how mechanistic understanding of the role of...

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Identifiers

PMID: 30028006
DOI: 10.1002/cpt.1185

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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