Drug transporters and anthracycline-induced cardiotoxicity.

Abstract excerpt

The solute carrier superfamily comprises of uptake transporters that can contribute to the absorption and elimination of a broad array of clinically important drugs. Recent studies have suggested that the tissue-specific expression of these transporters may have important consequences for an individual's susceptibility to drug-induced organ damage or to drug-drug interactions. Polymorphic variants have been...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Anthracyclines
• Share to Biological Transport
• Share to Cardiotoxicity