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Article

Molecular Modeling of Drug-Transporter Interactions-An International Transporter Consortium Perspective.

Clinical pharmacology and therapeutics - 1 Nov 2018

Schlessinger Avner, Welch Matthew A, van Vlijmen Herman, Korzekwa Ken, Swaan Peter W, Matsson Pär

Abstract excerpt

Membrane transporters play diverse roles in the pharmacokinetics and pharmacodynamics of small-molecule drugs. Understanding the mechanisms of drug-transporter interactions at the molecular level is, therefore, essential for the design of drugs with optimal therapeutic effects. This white paper examines recent progress, applications, and challenges of molecular modeling of membrane transporters, including...

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Source

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Identifiers

PMID: 29981151
DOI: 10.1002/cpt.1174
PMCID: PMC6197929

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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