Article
Systematic Evaluation of Genetic Variants for Polycystic Ovary Syndrome in a Chinese Population.
PloS one - 1 Jan 2015
Xu Yuping, Li Zhiqiang, Ai Fenglian, Chen Jianhua, Xing Qiong, Zhou Ping, Wei Zhaolian, Shi Yongyong, He Xiao-Jin, Cao Yunxia
Abstract excerpt
To date, eleven genome-wide significant (GWS) loci (P < 5×10-8) for polycystic ovary syndrome (PCOS) have been identified through genome-wide association studies (GWAS). Some of the risk loci have been selected for replications and validated in multiple ethnicities, however, few previous studies investigated all loci. Scanning all the GWAS variants would demonstrate a more informative profile of variance they...
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