Article
Genetic association between LHCGR variants and polycystic ovary syndrome: a meta-analysis.
Journal of assisted reproduction and genetics - 1 Apr 2025
Singh Sukhjashanpreet, Kaur Mandeep, Thapar Pallvi, Kaur Anupam
Abstract excerpt
BACKGROUND: The luteinizing hormone/choriogonadotropin receptor (LHCGR) is mapped at the 2p16.3 region, which was identified as a PCOS-susceptible locus in the first genome-wide association study (GWAS). Since then, several variants of LHCGR have been documented as susceptible loci for the development of PCOS, with striking differences due to diverse racial backgrounds. The present meta-analysis was conducted to...
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