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Article

The Prognostic Role of SIRT1-Autophagy Axis in Gastric Cancer

1 Jan 2016

Abstract excerpt

Aim. Sirtuin 1 (SIRT1) can induce autophagy through deacetylation of Beclin-1 and other autophagy mediators. However, the relationship between SIRT1 and autophagy in GC has not been defined. Therefore, the aim of this study was to confirm the prognostic value of SIRT1 and Beclin-1 and their relationship in GC patients. Methods. Transmission electron microscopy (TEM) was performed to examine the autophagy in GC...

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Identifiers

PMID: 28070138
DOI: 10.1155/2016/6869415

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