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Article

SIRT5 regulates autophagy and apoptosis in gastric cancer cells

1 Feb 2021

Abstract excerpt

OBJECTIVE: Accumulating evidence illustrates that sirtuins (SIRTs) regulate autophagy and apoptosis in cancer cells; however, the role of SIRT5 in gastric cancer (GC) cells remains unknown. In this study, we examined the role of SIRT5 in GC cells. METHODS: We detected SIRT5 protein levels in freshly collected samples from patients with GC. Next, we studied the function of SIRT5 in autophagy. Furthermore, the...

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PMID: 33530803
DOI: 10.1177/0300060520986355

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