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Article

DNA methylation changes at TREM2 intron 1 and TREM2 mRNA expression in patients with Alzheimer's disease.

Journal of psychiatric research - 1 Sept 2017

Ozaki Yuki, Yoshino Yuta, Yamazaki Kiyohiro, Sao Tomoko, Mori Yoko, Ochi Shinichiro, Yoshida Taku, Mori Takaaki, Iga Jun-Ichi, Ueno Shu-Ichi

Abstract excerpt

OBJECTIVES: Recent genome-wide association studies revealed that Triggering receptor expressed on myeloid cells 2 (TREM2) was associated with Alzheimer's disease (AD) and other neurodegenerative diseases. We previously reported that TREM2 mRNA is highly expressed in leukocytes of AD patients compared to those in healthy controls. However, the mechanism of TREM2 expression change is still not known. In this study,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28412600
DOI: 10.1016/j.jpsychires.2017.04.003

Genes

TREM2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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