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Article

Aging modulates microglia phenotypes in neuroinflammation of MPTP-PD mice.

Experimental gerontology - 1 Oct 2018

Yao Kai, Zhao Yong-Fei

Abstract excerpt

As the crucial etiological factor, aging-related microglia activation promotes the development of Parkinson's disease (PD). However, the molecular and functional changes of aged-microglia and their contribution to neurodegeneration in PD are only partially understood, which was investigated in our study. Female C57BL/6 mice were randomly divided into four groups, included young-control group, young-MPTP group,...

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Identifiers

PMID: 30009921
DOI: 10.1016/j.exger.2018.07.010

Genes

TLR2
TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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