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Article

Telomerase promoter mutations and copy number alterations in solitary fibrous tumours.

Journal of clinical pathology - 1 Sept 2018

Lin Yingbo, Seger Nelly, Tsagkozis Panagiotis, Hesla Asle C, Ghaderi Mehran, Chen Yi, Ehnman Monika, Warsito Dudi, Wejde Johan, Larsson Olle, Haglund Felix

Abstract excerpt

AIMS: Solitary fibrous tumour (SFT) is an infrequently metastasising mesenchymal tumour defined by the NAB2-STAT6 fusion gene. Activating mutations in the telomerase reverse transcriptase (hTERT) gene promoter has been reported to associate with adverse patient outcome in SFTs. METHODS: We analysed the hTERT gene for promoter mutations and copy number alterations in 43 primary extrameningeal SFTs (9 malignant and...

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Source

Identifiers

PMID: 29703757
DOI: 10.1136/jclinpath-2018-205132

Genes

NAB2
STAT6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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