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RpoB mutation patterns in Rifampicin-resistant tuberculosis: a Jiangxi Province study, 2021–2023

31 Jul 2025

Abstract excerpt

Antimicrobial resistance in Mycobacterium tuberculosis (M.tb) strains presents a significant challenge to global tuberculosis (TB) control efforts. This study was conducted to explore the distribution and prevalence of mutations at various sites within the 81 bp Rifampicin (RIF) resistance-determining region (RRDR) of the rpoB gene in M.tb, as detected by the Xpert MTB/RIF assay. This retrospective analysis...

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PMID: 40745428
DOI: 10.1038/s41598-025-11949-0

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